top of page
tissues.jpg
Self-Assembly (SA)

The SA model was designed to specifically model the dermal layer of the tissue in a higher throughput format. By utilizing a fully human and fibroblast specific extracellular matrix, this system is able to better model dermal disease phenotypes and responses to therapeutics

SkinmodelSA.jpg
SAfig.png

Fibroblast produced dermis

       Applications

  • Disease modeling

  • Dermal response

  • Mouse xenografting

       Cell Types​

  • Fibroblasts

  • Monocytes

       Readouts

  • Histology 

  • Immunohistochemistry

  • Extracellular matrix production and organization

  • Extracellular matrix components 

  • Tissue stiffness and contraction

  • Protein expression

  • Gene expression

  • Cytokine secretion

Contact Us

​

Tufts University School of Dental Medicine

Department of Diagnostic Sciences

136 Harrison Ave. 

South Cove Building, Room 116 

Boston, MA 02111

​

Tel: 617-636-2478

​

Email us: garlicklab@tufts.edu

© 2023 Nathan Ashby

tuftssdm.png
bottom of page