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Human Skin Equivalent (HSE)

The HSE model has been our gold standard for over 20 years. This model stands out in its ability to model cell-cell and cell-stimulus interactions in-situ.  

Full thickness epidermis

Dermal layer with fibroblasts

       Applications

  • Wound Healing

  • UV protection

  • Disease modeling

  • HSE on mouse xenografting

  • Psoriasis/Dandruff

  • Cytotoxicity

  • Keratinocyte proliferation/differentiation

       Cell Types

  • Keratinocytes

  • Fibroblasts

  • Monocytes

  • Melanocytes

       Readouts

  • Histology 

  • Immunohistochemistry

  • Tissue stiffness and contraction

  • Protein expression

  • Gene expression

  • Cytokine secretion

 Contact Us

Tufts University School of Dental Medicine

Department of Diagnostic Sciences

136 Harrison Ave. 

South Cove Building, Room 116 

Boston, MA 02111

Tel: 617-636-2478

Email us: garlicklab@tufts.edu

 

© 2019 Nathan Ashby

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